MECHANISM OF ACTION OF SILDENAFIL CITRATE

Sildenafil Citrate is the most well known and most widely used erectile dysfunction medication available today. The main mechanism of action of this anti-impotency drug is it acts as a vasodilator. It enlarges the lumen and size of the arteries and veins by directly relaxing the smooth muscles of these arteries and veins. Aside from its general vasodilating effect, it has a relatively specific organ target in that it selectively dilates to a greater extent the penile vasculature in contrast to the general vasculature. This leads to penile erection without much effect on blood pressure and cardiac rate and rhythm. It is this characteristic of the drug which makes it the most widely used and most acceptable erectile dysfunction drug among those available such as Levitra, Cialis, Extense and a lot of other similar medications.

The most common cause of impotency and erectile dysfunction is aging where the arteries become thickened and lose their elasticity. Aging also results in the accumulation of fat along the walls of the blood vessels, a condition known as atherosclerosis. These conditions contribute to the inability to have an erection or to sustain one. This results in the need to buy Levitra. Aside from aging, a very common organic cause of impotency or erectile dysfunction is the metabolic disorder known as Diabetes Mellitus. In this metabolic disorder, there is a multi-organ involvement including the kidneys, the heart and the circulatory system in general. This is where Sildenafil Citrate becomes very effective in correcting or alleviating the defect or defects. Try to buy Sildenafil Citrate now and get over that erectile dysfunction problem.